Saturday, October 5, 2013

Moms For Marijuana Push For Legal Cannabis, For the Children

source: Hit & Run

Bomb Seeds

It’s a far cry from MADD. Valley News Live, the NBC/CBS affiliate in North Dakota spotlights a local mom that’s part of Moms for Marijuana, a grassroots legalization group:
disclosure: i'm not a mom"It's the old reefer madness, you know, doing what you've been told for years, it's bad it's bad so therefore it is bad, do your research, ask somebody about it." [local mom] Patty [Mary] urges.

Fargo Police say all drugs have negative affects to the community, but Patty says she focuses on the positives of the plant she believes in.

"You'd be amazed, there are little kids that are being saved from seizures." She says.
While Patty seems to focus on the medicinal benefits of marijuana, the group’s website spells out that the mothers’ position on cannabis is:
*-That the Cannabis plant is a renewable, sustainable, and versatile resource that has been overlooked and distorted for too long. All around the world, the truth about Cannabis is being realized and it is time for our governments to start discussing and changing all Cannabis laws to reflect the will of the people.

-That our governments should research and utilize all the potential benefits of this plant, and encourage locally grown Cannabis products be made available to the public through a taxed and regulated market.

-That as with all drugs, Marijuana should not be used by developing minds under the age of legal consent, without parental guidance, as well as the recommendation and continous [sic] evaluation by a licensed medical physician.

-That the access our children have to the drug, Marijuana, can be drastically reduced through legalization and regulation. In order to keep this drug out of the hands of our kids, Marijuana needs to be taken off of streets and away from the black market.
The “for the children” argument for marijuana legalization is not new. The participation of mothers in the debate over marijuana legalization is certainly an indicator that the issue is firmly in the mainstream political discourse.
More about Moms for Marijuana here. More Reason on marijuana here.

 Epilepsy is a common and diverse set of chronic neurological disorders characterized by seizures. Some definitions of epilepsy require that seizures be recurrent and unprovoked, but others require only a single seizure combined with brain alterations which increase the chance of future seizures.

In many cases a cause cannot be identified; however, factors that are associated include brain trauma, strokes, brain cancer, and drug and alcohol misuse among others.

EPILEPSY/ SEIZURES & Cannabis studies completed

Undated - Anecdotal ~ Marijuana and Epilepsy.
1980 - Study - Chronic administration of cannabidiol to healthy volunteers and epileptic patients.
1981 - Study - Hypnotic and Antiepileptic Effects of Cannabidiol.
1981 - Study ~ Antiepileptic potential of cannabidiol analogs.
1981 - Study ~ The cannabinoids as potential antiepileptics.
1982 - Study ~ Anticonvulsant effects of the (-) and (+)isomers of cannabidiol and their dimethylheptyl homologs.
1982 - Study ~ Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice.
1992 - Study ~ Marijuana use and the risk of new onset seizures.
1999 - Study - Therapeutic Aspects of Cannabis and Cannabinoids.
2001 - Study ~ Anticonvulsant activity of N-palmitoylethanolamide, a putative endocannabinoid, in mice.
2001 - Study ~ Alcohol and marijuana: effects on epilepsy and use by patients with epilepsy.
2003 - Study ~ The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy.
2003 - Study ~ On the application of cannabis in paediatrics and epileptology.
2003 - Study - Experiences with THC-treatment in children and adolescents.
2003 - Article - Marijuana and Epilepsy.
2003 - News - Marijuana Use More Prevalent With Epilepsy.
2003 - News - Cannabis may help epileptics.
2004 - Study - Endocannabinoids and Their Implications for Epileps.
2004 - Study ~ Cannabinoids: Defending the Epileptic Brain.
2004 - Study ~ Marijuana use and epilepsy - Prevalence in patients of a tertiary care epilepsy center.
2004 - News - Epilepsy patients are smoking pot.
2005 - Study ~ Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid.
2005 - Study - Treatment with CBD in oily solution of drug-resistant paediatric epilepsies.
2005 - Study ~ Cannabinoids as potential anti-epileptic drugs.
2006 - Study ~ Not Too Excited? Thank Your Endocannabinoids.
2006 - Study ~ Forebrain-Specific Inactivation of Gq/G11 Family G Proteins Results in Age-Dependent Epilepsy and Impaired Endocannabinoid Formation.
2006 - Study ~ The Endocannabinoid System Controls Key Epileptogenic Circuits in the Hippocampus.
2006 - Study ~ Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy.
2006 - Study ~ Activation of the Cannabinoid Type-1 Receptor Mediates the Anticonvulsant Properties of Cannabinoids in the Hippocampal Neuronal Culture Models of Acquired Epilepsy and Status Epilepticus.
2006 - Study ~ Cannabinoids In Medicine: A Review Of Their Therapeutic Potential.
2006 - Study ~ Arachidonyl-2'-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshock-induced seizure model.
2006 - News ~ Brain's Cannabinoid System 'Mellows' Seizures.
2006 - News ~ Brain's cannabinoid system fights seizures.
2007 - Study - Marijuana: an effective antiepileptic treatment in partial epilepsy?
2007 - Study ~ Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus.
2007 - Study ~ Endocannabinoids block status epilepticus in cultured hippocampal neurons.
2007 - Study ~ Downregulation of the CB1 Cannabinoid Receptor and Related Molecular Elements of the Endocannabinoid System in Epileptic Human Hippocampus.
2007 - Study ~ Ultra-low dose cannabinoid antagonist AM251 enhances cannabinoid anticonvulsant effects in the pentylenetetrazole-induced seizure in mice.
2007 - News ~ Rimonabant: safety issues.
2008 - Study ~ The phytocannabinoid Delta(9)-tetrahydrocannabivarin modulates inhibitory neurotransmission in the cerebellum.
2008 - Study ~ The cannabinoid anticonvulsant effect on pentylenetetrazole-induced seizure is potentiated by ultra-low dose naltrexone in mice.
2009 - Study ~ The effects of intracerebroventricular AM-251, a CB1-receptor antagonist, and ACEA, a CB1-receptor agonist, on penicillin-induced epileptiform activity in rats.
2009 - Study ~ Prolonged exposure to WIN55,212-2 causes downregulation of the CB1 receptor and the development of tolerance to its anticonvulsant effects in the hippocampal neuronal culture model of acquired epilepsy.
2009 - Study ~ Effect of arachidonyl-2'-chloroethylamide, a selective cannabinoid CB1 receptor agonist, on the protective action of the various antiepileptic drugs in the mouse maximal electroshock-induced seizure model.
2009 - Study ~ Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB(1) agonist ACEA in the pentylenetetrazole-induced seizure in mice.
2009 - News ~ Medical Marijuana and Epilepsy.
2010 - Study ~ Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo.
2010 - Study ~ Cannabinoid-mediated inhibition of recurrent excitatory circuitry in the dentate gyrus in a mouse model of temporal lobe epilepsy.
2010 - Study ~ AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity.
2010 - Study ~ Delta-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats.
2010 - Study ~ Anticonvulsant effects of GWP42006 in vitro and in vivo in rat.
2010 - Study ~ Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans.
2011 - Study ~ Endocannabinoid system protects against cryptogenic seizures.
2011 - Study ~ Convulsions Associated with the Use of a Synthetic Cannabinoid Product.
2011 - Study ~ Pro-epileptic effects of the cannabinoid receptor antagonist SR141716 in a model of audiogenic epilepsy.
2011 - Study ~ Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
2011 - Study ~ Protective effects of CB1 receptor agonist WIN 55.212-2 in seizure activity in the model of temporal lobe epilepsy.
2011 - Study ~ L-Type Calcium Channel Mediates Anticonvulsant Effect of Cannabinoids in Acute and Chronic Murine Models of Seizure.
2011 - Study ~ Changes in the cannabinoid (CB1) receptor expression level and G-protein activation in kainic acid induced seizures.
2011 - Study ~ Marijuana, endocannabinoids, and epilepsy: Potential and challenges for improved therapeutic intervention.
2011 - News ~ Cannabis could help treat epilepsy.
2011 - News ~ Cannabis could be used to treat epilepsy.
2011 - News ~ New research provides hope for those with epilepsy.
2012 - Patent Application ~ Use of the phytocannabinoid cannabidivarin (cbdv) in the treatment of epilepsy: Patent Application 20120004251
2012 - Study ~ Inverse relationship of cannabimimetic (R+)WIN 55, 212 on behavior and seizure threshold during the juvenile period.
2012 - Study ~ Equipotent Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase - Dual Targets of the Endocannabinoid System to Protect against Seizure Pathology.
2012 - Study ~ Epileptiform activity in the CA1 region of the hippocampus becomes refractory to attenuation by cannabinoids in part because of endogenous γ-aminobutyric acid type B receptor activity.
2012 - Study ~ Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?
2012 - Study ~ Statistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain.
2012 - Study ~ Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures.
2012 - Study ~ Internet Highs-Seizures After Consumption of Synthetic Cannabinoids Purchased Online.
2012 - Study ~ Cannabinoid receptor 1 inhibition causes seizures during anesthesia induction in experimental sepsis.
2012 - Study ~ Effect of ACEA-a selective cannabinoid CB1 receptor agonist on the protective action of different antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model.
2012 - Study ~ Hammer Head' 'incense' blamed for seizure of youth in Le Roy.

Epilepsy Hardcover Books
Wyllie's Treatment of Epilepsy: Principles and Practice (Wyllie, Treatment of Epilepsy)Seizures and Epilepsy in Childhood: A Guide (Johns Hopkins Press Health Book)The Causes of Epilepsy: Common and Uncommon Causes in Adults and Children (Cambridge Medicine)Epilepsy Explained: A Book for People Who Want to Know MoreTreating Epilepsy Naturally : A Guide to Alternative and Adjunct TherapiesEpilepsy: Patient and Family Guide

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